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This editorial describes a supplement of the Journal of Interprofessional Care (JIC) which contains the 380 abstracts accepted for Collaborating Across Borders III (CAB III), a biennial US-Canadian conference, which was held in Tucson, Arizona on November 19-21, 2011. It was co-hosted by the American Interprofessional Health Collaborative (AIHC) (American Interprofessional Health Collaborative, 2012) and Canadian Interprofessional Health Collaborative (CIHC) (Canadian Interprofessional Health Collaborative, 2012), in collaboration with The University of Arizona Health Sciences Center, the Arizona Telemedicine Program, and the University of Minnesota Academic Health Center.

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