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This video (1:26:39 minutes) is a presentation given by Jonathan Drake in which he discusses lifestyle risk factors for dementia. Main points of the presentation includes: (1) defining Alzheimer's disease and dementia; (2) the evolving science of Alzheimer's disease; (3) why white matter of the brain matters (blood vessels and inflammation); (4) vascular risk factors and dementia risk; (5) multifactorial risk and the science of aging; and (6) the optimism within this field of research.