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This lecture (53:58 minutes) given by Jeannie K. Lee discusses medications in the context of the age friendly health systems 4Ms. By the end of this lecture, learners should be able to: (1) describe medication as part of the 4Ms of the age-friendly health system; (2) discuss opportunities to integrate medication when moving toward the age-friendly health system; (3) identify ways to incorporate medication into age-friendly health systems; and (4) list examples of evidence-based tools for addressing polypharmacy and deprescribing.